The general biology of the common
primary brain tumors is reviewed, as are the results of surgery,
radiation therapy, and
chemotherapy for these
neoplasms. The problems of classification, particularly of the
astrocytomas, are noted, with the resultant difficulties in comparing different series. The development and consistent application of a widely acceptable nomenclature for
brain tumors would be useful in the comparison of various
therapies and for ease in communication. Further, a better general understanding of the biology of the various
brain tumors is desirable. Reliable data relative to old or new forms of
therapy seem to require national or regional studies in view of the relative rarity of some of these
tumors. Except for
medulloblastoma, the best results of
therapy thus far are only slightly encouraging. We must also be aware that some of our treatments may do as much harm to some patients as their
tumors; therefore, we must all strive for a high autopsy rate so that we can monitor our
therapy and recognize unexpected complications as quickly as possible.