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Outbreak of Panton-Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus in a regional burns unit.

Abstract
Over a 16 month period, 30 individuals (19 patients, one relative and 10 members of staff) on a regional burns and plastics unit became colonised or infected with a single strain of Panton-Valentine leucocidin-producing meticillin-resistant Staphylococcus aureus (PVL-MRSA). The strain was resistant to ciprofloxacin, neomycin and gentamicin and belonged to a community-associated MRSA lineage known to be circulating in the UK. The outbreak occurred in four stages, the first being in burns outpatients, the second and third being on the burns unit itself and the final stage on a plastics ward. In spite of closing the affected unit and deep cleaning, including steam cleaning and hydrogen peroxide treatment, the outbreak continued. It was not until staff carriage was fully addressed that the outbreak was controlled.
AuthorsL Teare, O P Shelley, S Millership, A Kearns
JournalThe Journal of hospital infection (J Hosp Infect) Vol. 76 Issue 3 Pg. 220-4 (Nov 2010) ISSN: 1532-2939 [Electronic] England
PMID20619492 (Publication Type: Journal Article)
CopyrightCopyright © 2010 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.
Chemical References
  • Anti-Bacterial Agents
  • Bacterial Toxins
  • Exotoxins
  • Leukocidins
  • Panton-Valentine leukocidin
Topics
  • Anti-Bacterial Agents (pharmacology)
  • Bacterial Toxins (metabolism)
  • Burn Units (statistics & numerical data)
  • Carrier State (epidemiology, microbiology, prevention & control)
  • Cross Infection (epidemiology, microbiology, prevention & control)
  • Disease Outbreaks (prevention & control)
  • Drug Resistance, Multiple, Bacterial
  • Exotoxins (metabolism)
  • Health Personnel
  • Humans
  • Leukocidins (metabolism)
  • Mass Screening
  • Methicillin-Resistant Staphylococcus aureus (drug effects, isolation & purification)
  • Microbial Sensitivity Tests
  • Staphylococcal Infections (epidemiology, microbiology)
  • Surveys and Questionnaires
  • United Kingdom (epidemiology)

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