Ubiquitin recognition by the Cockayne syndrome group B protein: binding will set you free.

Abstract

Transcription-coupled nucleotide excision repair (TC-NER) requires the coordinated efforts of many proteins. In this issue of Molecular Cell, Anindya et al. (2010) show that the proteins assemble at the site of DNA damage but cannot begin repair until the Cockayne syndrome group B protein (CSB) binds ubiquitin.

• Authors: Lucas T Gray, Alan M Weiner
• Journal: Molecular cell (Mol Cell) Vol. 38 Issue 5 Pg. 621-2 (Jun 11 2010) ISSN: 1097-4164 [Electronic] United States
• PMID: 20541993 (Publication Type: Comment, Journal Article)
• Copyright: Copyright (c) 2010 Elsevier Inc. All rights reserved.