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Total intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case report-.

Abstract
A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome.
AuthorsJin Suk Park, Chong Wha Baek, Hyun Kang, Su Man Cha, Jung Won Park, Yong Hun Jung, Young-Cheol Woo
JournalKorean journal of anesthesiology (Korean J Anesthesiol) Vol. 58 Issue 4 Pg. 409-12 (Apr 2010) ISSN: 2005-7563 [Electronic] Korea (South)
PMID20508802 (Publication Type: Journal Article)

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