Abstract | BACKGROUND: Ovarian follicular cyst producing estradiol is a rare cause of isosexual pseudoprecocious puberty. Intense pigmentation of breast papillae, areolae, and labia minora is also rarely reported in the literature. CASE: SUMMARY AND CONCLUSION: High levels of circulating estradiol due to an ovarian follicle can induce precocious puberty and pigmentation of the skin which regresses after surgical removal of the cyst. Elevated DHEAS levels may be the initiating event causing the formation of the large follicular cyst.
|
Authors | Ioannis Biliatis, Nikolaos Thomakos, Chrisoula Panitsa Faflia, Nikolaos Akrivos, Aris Antsaklis |
Journal | Journal of pediatric and adolescent gynecology
(J Pediatr Adolesc Gynecol)
Vol. 23
Issue 5
Pg. e145-8
(Oct 2010)
ISSN: 1873-4332 [Electronic] United States |
PMID | 20493737
(Publication Type: Case Reports, Journal Article)
|
Copyright | Copyright © 2010 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved. |
Chemical References |
|
Topics |
- Age Determination by Skeleton
- Androsterone
(metabolism)
- Child, Preschool
- Estradiol
(metabolism)
- Female
- Follicular Cyst
(complications, metabolism)
- Humans
- Ovarian Cysts
(complications, metabolism)
- Puberty, Precocious
(etiology)
- Skin Pigmentation
|