Orbital lymphoma masquerading as panuveitis.

Abstract

PURPOSE:

To describe a case of orbital mucosa-associated lymphoid tissue (MALT) lymphoma masquerading as unilateral panuveitis.

METHODS:

Retrospective chart review.

RESULTS:

A 53-year-old female patient with unilateral vitritis and exudative retinal detachment refractory to immunosuppressive treatment was eventually diagnosed with orbital MALT lymphoma. Following treatment with radiotherapy and rituximab, the patient's intraocular inflammation and retinal detachment resolved.

CONCLUSIONS:

Orbital MALT lymphoma can masquerade as refractory unilateral panuveitis with exudative retinal detachment and appears to respond to a combination of radiotherapy and specific B-cell-targeted systemic therapy.

• Authors: Puneet Panda, Farzin Forooghian, Todd Goodglick, Chi-Chao Chan, Robert Nussenblatt, H Nida Sen
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 18 Issue 3 Pg. 181-3 (Jun 2010) ISSN: 1744-5078 [Electronic] England
• PMID: 20482392 (Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Intramural, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Monoclonal, Murine-Derived
• Antineoplastic Agents
• Rituximab

Topics

• Antibodies, Monoclonal, Murine-Derived (therapeutic use)
• Antineoplastic Agents (therapeutic use)
• Diagnosis, Differential
• Female
• Fluorescein Angiography
• Follow-Up Studies
• Fundus Oculi
• Humans
• Lymphoma, B-Cell, Marginal Zone (complications, diagnosis, therapy)
• Middle Aged
• Orbital Neoplasms (complications, diagnosis, therapy)
• Panuveitis (diagnosis, etiology)
• Radiotherapy, Adjuvant
• Rituximab
• Tomography, Optical Coherence
• Tomography, X-Ray Computed