Abstract | BACKGROUND: MATERIALS AND METHODS: RESULTS: We found no correlation of EGF, EGFR, c-erbB-2, Bax and Bcl-xL with age and gender of patients, or histological type and grade of malignancy (G). However, we observed a very strong correlation between EGF, EGFR, Bax, Bcl-xL and lymph node metastases (p=0.000, p=0.001, p=0.008, p=0.012, respectively) and between EGF, EGFR and distant metastases (p=0.002, p=0.008, respectively). Moreover, we found a correlation between Bcl-xL and c-erbB-2 (p=0.030) and between EGF and Bax (p=0.041). CONCLUSIONS:
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Authors | Anna Pryczynicz, Katarzyna Guzińska-Ustymowicz, Jolanta Czyzewska, Andrzej Kemona |
Journal | Folia histochemica et cytobiologica
(Folia Histochem Cytobiol)
Vol. 47
Issue 4
Pg. 667-71
( 2009)
ISSN: 1897-5631 [Electronic] Poland |
PMID | 20430737
(Publication Type: Journal Article)
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Chemical References |
- BCL2L1 protein, human
- Biomarkers, Tumor
- Proto-Oncogene Proteins c-bcl-2
- bcl-2-Associated X Protein
- bcl-X Protein
- Epidermal Growth Factor
- ErbB Receptors
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Topics |
- Adult
- Aged
- Apoptosis
(physiology)
- Biomarkers, Tumor
(metabolism)
- Carcinoma, Pancreatic Ductal
(metabolism, pathology)
- Epidermal Growth Factor
(metabolism)
- ErbB Receptors
(metabolism)
- Female
- Humans
- Male
- Middle Aged
- Pancreatic Neoplasms
(metabolism, pathology)
- Proto-Oncogene Proteins c-bcl-2
(metabolism)
- bcl-2-Associated X Protein
(metabolism)
- bcl-X Protein
(metabolism)
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