Characterization of three Staphylococcus aureus isolates from a 17-year-old female who died of tampon-related toxic shock syndrome.

Abstract	We report the identification and characterization of three Staphylococcus aureus isolates recovered from throat and vaginal cultures, as well as from an axillary abscess, of a 17-year-old female who died of tampon-related toxic shock syndrome. The three S. aureus isolates were unrelated as determined by pulsed-field gel electrophoresis. The vaginal isolate was mecA, Panton-Valentine leukocidin, and staphylococcal enterotoxin B and C negative, toxic shock syndrome toxin 1 positive, and staphylococcal cassette chromosome mec element (SCCmec) untypeable, which was consistent with the clinical and autopsy findings that death was due to tampon-related toxic shock syndrome.
Authors	Yi-Wei Tang, Eric Himmelfarb, Marcia Wills, Charles W Stratton
Journal	Journal of clinical microbiology (J Clin Microbiol) Vol. 48 Issue 5 Pg. 1974-7 (May 2010) ISSN: 1098-660X [Electronic] United States
PMID	20351214 (Publication Type: Case Reports, Journal Article)
Chemical References	Bacterial Proteins Bacterial Toxins Enterotoxins Exotoxins Leukocidins Panton-Valentine leukocidin Penicillin-Binding Proteins Superantigens enterotoxin F, Staphylococcal mecA protein, Staphylococcus aureus enterotoxin B, staphylococcal enterotoxin C, staphylococcal
Topics	Abscess (microbiology) Adolescent Axilla (microbiology) Bacterial Proteins (genetics) Bacterial Toxins (genetics) Bacterial Typing Techniques Cluster Analysis DNA Fingerprinting Electrophoresis, Gel, Pulsed-Field Enterotoxins (genetics) Exotoxins (genetics) Fatal Outcome Female Humans Leukocidins (genetics) Menstrual Hygiene Products (adverse effects) Penicillin-Binding Proteins Pharynx (microbiology) Shock, Septic (microbiology) Staphylococcal Infections (complications, microbiology) Staphylococcus aureus (isolation & purification) Superantigens (genetics) Vagina (microbiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!