Palindromic rheumatism: a response to chloroquine.

Abstract	We reviewed 71 patients with palindromic rheumatism. The average length of followup was 3.6 years. Fifty-one patients received antimalarial therapy. Forty-one of the 51 patients experienced marked improvement with 77.5% reduction in frequency and 63% reduction in duration of attacks. Sixteen out of the 71 patients developed persistent arthritis in the form of rheumatoid arthritis (12 patients), systemic lupus erythematosus (2 patients), Crohn's disease (1 patient) and asymmetric seronegative arthropathy (1 patient). Chloroquine therapy, therefore, seems effective in relieving palindromic rheumatism.
Authors	W Youssef, A Yan, A S Russell
Journal	The Journal of rheumatology (J Rheumatol) Vol. 18 Issue 1 Pg. 35-7 (Jan 1991) ISSN: 0315-162X [Print] Canada
PMID	2023196 (Publication Type: Clinical Trial, Journal Article)
Chemical References	Antimalarials Chloroquine
Topics	Adolescent Adult Aged Antimalarials (therapeutic use) Child Chloroquine (therapeutic use) Female Humans Male Middle Aged Rheumatic Diseases (drug therapy, physiopathology)

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