HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Intrastromal corneal ring segment SK implantation for moderate to severe keratoconus.

AbstractPURPOSE:
To report the efficacy and safety of intrastromal corneal ring segment (ICRS) implantation using a femtosecond laser in the management of advanced keratoconus.
SETTING:
Private laser center, Toronto, Ontario, Canada.
METHOD:
In this retrospective nonrandomized study, Intacs SK ICRS were implanted using an IntraLase femtosecond laser in eyes with moderate to severe keratoconus. Evaluation included uncorrected (UDVA) and corrected (CDVA) distance visual acuity, manifest refraction, slitlamp examination, corneal topography, and wavefront analysis of higher-order aberrations. Postoperative visits were at 1, 7, and 30 days and 3 and 6 months.
RESULTS:
The study evaluated 10 eyes of 8 patients with a mean age of 28 years (range 21 to 42 years). The mean UDVA was significantly better 6 months postoperatively than preoperatively (0.66 logMAR +/- 0.21 [SD] versus 1.19 +/- 0.57 logMAR) (P = .004), as was the mean CDVA (0.25 +/- 0.15 logMAR versus 0.51 +/- 0.20 logMAR) (P = .018). The mean spherical equivalent refractive error was -8.08 diopters (D) preoperatively and -5.03 D at 6 months (P = .65); the mean refractive astigmatism, -5.05 D and -3.90 D, respectively (P = .22); and the mean simulated keratometry value, 57.94 D and 50.07 D, respectively (P = .15). The mean total aberration improved significantly, from 13.48 +/- 4.64 mum preoperatively to 9.42 +/- 1.80 mum postoperatively (P = .007). There were no complications.
CONCLUSION:
Implantation of ICRS for advanced keratoconus was safe and effective, leading to significant improvement in UDVA, CDVA, and total aberrations.
FINANCIAL DISCLOSURE:
No author has a financial or proprietary interest in any material or method mentioned.
AuthorsWiwan Sansanayudh, Irit Bahar, Nikhil L Kumar, Raneen Shehadeh-Mashour, Rusty Ritenour, Neera Singal, David S Rootman
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 36 Issue 1 Pg. 110-3 (Jan 2010) ISSN: 1873-4502 [Electronic] United States
PMID20117713 (Publication Type: Journal Article)
CopyrightCopyright 2010 ASCRS and ESCRS. All rights reserved.
Topics
  • Aberrometry
  • Adult
  • Corneal Stroma (physiopathology, surgery)
  • Corneal Topography
  • Corneal Wavefront Aberration (physiopathology)
  • Female
  • Humans
  • Keratoconus (physiopathology, surgery)
  • Male
  • Prostheses and Implants
  • Prosthesis Implantation
  • Refraction, Ocular (physiology)
  • Retrospective Studies
  • Visual Acuity (physiology)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: