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[A case of recurrence gastric cancer patient who was post operated and multi drug chemotherapy was effective for administration of S-1 and docetaxel combination therapy].

Abstract
Recently, chemotherapy against gastric cancer has been diversified with an appearance of new agents such as S-1, capecitabine, CPT-11, oxaliplatin, paclitaxel and docetaxel. But a prognosis of advanced or recurrent gastric cancer patient, who was failure of first- and second-line chemotherapy, was poor. We reported that a case of recurrence gastric cancer patient who was post operated and multi drug chemotherapy was effective for administration of S-1 and docetaxel combination therapy. A case was a 50-year-old man. He underwent distal gastrectomy and administered of multi anticancer drugs until about eight years after operation. But multi lung and liver and lymph-node metastases were appeared. We administered S-1 and docetaxel combination chemotherapy. After two courses, multi metastatic lesions were reduced in size, and tumor markers were decreased. The same combination therapy was administered for six courses, but metastatic lesions were increased again. At one hundred four months after the operation, he died in the palliative care unit.
AuthorsKatsunori Ami, Takeshi Nagahama, Toshiya Ohara, Hideaki Ganno, Kenichirou Hataji, Toshiaki Kurokawa, Akira Fukuda, Masayuki Andou, Shikofumi Tei, Kuniyoshi Arai
JournalGan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 36 Issue 12 Pg. 2336-8 (Nov 2009) ISSN: 0385-0684 [Print] Japan
PMID20037414 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antimetabolites, Antineoplastic
  • Antineoplastic Agents
  • Drug Combinations
  • Taxoids
  • S 1 (combination)
  • Tegafur
  • Docetaxel
  • Oxonic Acid
Topics
  • Antimetabolites, Antineoplastic (administration & dosage)
  • Antineoplastic Agents (administration & dosage)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Docetaxel
  • Drug Combinations
  • Gastrectomy
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Oxonic Acid (administration & dosage)
  • Stomach Neoplasms (drug therapy, surgery)
  • Taxoids (administration & dosage)
  • Tegafur (administration & dosage)

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