[A case of rectal cancer with lung metastases responding to cetuximab].

Abstract

We report a 73-year-old male patient who underwent low anterior resection for rectal cancer (Stage IIIb). Nine months after the surgery, multiple metastases of liver, lung, brain and lymph node were detected. He was treated with FOLFOX4 and FOLFIRI though lung metastases progressed and caused dyspnea. Cetuximab plus irinotecan therapy was dramatically effective, which improved his quality of life for over 10 months.

• Authors: Hiromi Kawai, Hiroyuki Uetake, Hirotoshi Kobayashi, Masayuki Enomoto, Tetsuro Higuchi, Masamichi Yasuno, Satoru Iida, Toshiaki Ishikawa, Kenichi Sugihara
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 36 Issue 12 Pg. 2152-4 (Nov 2009) ISSN: 0385-0684 [Print] Japan
• PMID: 20037353 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antibodies, Monoclonal
• Antibodies, Monoclonal, Humanized
• Antineoplastic Agents
• Antineoplastic Agents, Phytogenic
• Irinotecan
• Cetuximab
• Camptothecin

Topics

• Aged
• Antibodies, Monoclonal (administration & dosage)
• Antibodies, Monoclonal, Humanized
• Antineoplastic Agents (administration & dosage)
• Antineoplastic Agents, Phytogenic (administration & dosage)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Camptothecin (administration & dosage, analogs & derivatives)
• Cetuximab
• Humans
• Irinotecan
• Lung Neoplasms (drug therapy, secondary)
• Male
• Quality of Life
• Rectal Neoplasms (pathology, surgery)