Acellular dermal graft (AlloDerm) for upper eyelid reconstruction after cancer removal.

Abstract

PURPOSE:

To report the use of AlloDerm for reconstruction of large upper eyelid defects in cancer patients.

METHODS:

The clinical records of all patients who had AlloDerm as part of their upper eyelid reconstruction between July 2005 and July 2006 at a single institution were reviewed. Functional and cosmetic outcomes and postoperative complications were assessed.

RESULTS:

Two patients had recurrent sebaceous gland carcinoma, 2 had melanoma, and 1 had squamous cell carcinoma. The upper eyelid defect involved the full thickness and entire width of the upper eyelid in 4 patients and full thickness and two thirds of the upper eye eyelid in 1 patient. The reconstructive procedure included a modified Cutler-Beard procedure using AlloDerm as the posterior lamellar sandwich graft in all 5 patients. One patient had early postoperative adjuvant radiation therapy to the upper eyelid. Three patients had excellent functional and cosmetic outcome; 2 patients had satisfactory outcomes. Two patients had residual exposure keratopathy. Allergic reaction to AlloDerm, infectious transmission, and immunologic rejection were not encountered at the time of this report (mean follow-up time = 13 months).

CONCLUSIONS:

AlloDerm can be used as an alternative sandwich graft material to replace the tarsus for reconstruction of large upper eyelid defects using a modified Cutler-Beard procedure.

• Authors: Brent Hayek, Elham Hatef, Michael Nguyen, Viet Ho, Adam Hsu, Bita Esmaeli
• Journal: Ophthalmic plastic and reconstructive surgery (Ophthalmic Plast Reconstr Surg) 2009 Nov-Dec Vol. 25 Issue 6 Pg. 426-9 ISSN: 1537-2677 [Electronic] United States
• PMID: 19935241 (Publication Type: Journal Article)

Chemical References

• Alloderm
• Collagen

Topics

• Adenocarcinoma, Sebaceous (surgery)
• Aged
• Aged, 80 and over
• Carcinoma, Squamous Cell (surgery)
• Collagen (therapeutic use)
• Eyelid Neoplasms (surgery)
• Eyelids (surgery)
• Female
• Humans
• Male
• Melanoma (surgery)
• Middle Aged
• Ophthalmologic Surgical Procedures
• Plastic Surgery Procedures
• Retrospective Studies
• Skin, Artificial