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Gabapentin therapy for ocular opsoclonus-myoclonus restores eye movement communication in a patient with a locked-in syndrome.

Abstract
The experience with a patient with locked-in syndrome suffering from opsoclonus-myoclonus symptoms is described: gabapentin successfully reversed the symptoms, just favoring the regaining of eye-dependent communication strategies.
AuthorsFrancesca Pistoia, Marco Sarà
JournalNeurorehabilitation and neural repair (Neurorehabil Neural Repair) Vol. 24 Issue 5 Pg. 493-4 (Jun 2010) ISSN: 1552-6844 [Electronic] United States
PMID19933381 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Amines
  • Anticonvulsants
  • Cyclohexanecarboxylic Acids
  • gamma-Aminobutyric Acid
  • Gabapentin
Topics
  • Adult
  • Amines (therapeutic use)
  • Anticonvulsants (therapeutic use)
  • Cerebral Infarction (complications, pathology)
  • Cyclohexanecarboxylic Acids (therapeutic use)
  • Female
  • Gabapentin
  • Humans
  • Magnetic Resonance Imaging (methods)
  • Ocular Motility Disorders (drug therapy, etiology)
  • Opsoclonus-Myoclonus Syndrome (drug therapy, etiology)
  • Pons (pathology)
  • Quadriplegia (complications)
  • gamma-Aminobutyric Acid (therapeutic use)

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