High-intensity laser and photodynamic therapy as a treatment for recurrent herpes labialis.

Abstract

OBJECTIVE:

The aim of this study was to report the treatment of recurrent herpes labialis (RHL) using a high-intensity laser or methylene blue (MB)-mediated photodynamic therapy (PDT) in combination with low-level laser therapy (LLLT).

MATERIALS AND METHODS:

Four clinical cases of patients diagnosed with RHL are described in this report. Two patients were subjected to high-intensity laser therapy (HILT) followed by LLLT, and two patients received MB-mediated PDT, again followed by LLLT. LLLT was conducted at 24, 48, 72 h, and 7 d after HILT or PDT. Patients were followed up after 6 mo.

RESULTS:

Throughout the follow-up period, all patients reported pain relief and did not show any signs or symptoms of RHL. A favorable healing process was observed in all cases. None of the patients reported pain as a consequence of the treatment.

CONCLUSION:

These results suggest that HILT and MB-mediated PDT, in combination with LLLT, may constitute a benefit when treating vesicles in RHL.

• Authors: Juliana Marotti, Felipe Fornias Sperandio, Eduardo Rodrigues Fregnani, Ana Cecilia Corrêa Aranha, Patrícia Moreira de Freitas, Carlos de Paula Eduardo
• Journal: Photomedicine and laser surgery (Photomed Laser Surg) Vol. 28 Issue 3 Pg. 439-44 (Jun 2010) ISSN: 1557-8550 [Electronic] United States
• PMID: 19821702 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adolescent
• Combined Modality Therapy
• Female
• Herpes Labialis (radiotherapy)
• Humans
• Laser Therapy
• Low-Level Light Therapy
• Male
• Photochemotherapy
• Recurrence
• Wound Healing (radiation effects)
• Young Adult