Carotid angioplasty and stenting: lesion related treatment strategies.

Abstract

AIMS:

To evaluate the feasibility of lesion related treatment strategies in patients treated for severe carotid artery disease with angioplasty and stenting (CAS) under embolic protection devices (EPD).

METHODS AND RESULTS:

From December 2001 to August 2004 a total of 377 consecutive patients were enrolled to undergo CAS. The procedure was conducted by using several types of stents (cobalt-alloy frame, nitinol frame) and of EPD (filter-wires, proximal endovascular clamping devices) applied to specific lesions and/or anatomies.Primary endpoint was to assess the death and stroke rate at discharge.Secondary endpoints were to test the feasibility and safety of tailored CAS (angiographic success, any -complication between discharge and 30 days, death of any cause at 30 days).The procedural success was achieved in 377/377 patients (100%).Adverse events included:1. during procedure: 2 TIAs (0.53%)2. at discharge: 1 death procedure related (0.27%), 1 major stroke (0.27%), 2 minor strokes (0.53%), 4 TIAs (1.06%), 1 intracranial hemorrhage (0.27%); all adverse event rate at discharge 2.92%; all strokes and death rate at discharge 1.06%;3. at 30 day f.u.: one death not procedure related (0.27%), 1 minor stroke (0.27%);4. overall procedure related stroke and death rate: 1.33%.

CONCLUSIONS:

Our data suggest that using new materials/devices matched to specific lesions or anatomies is safe and effective.

• Authors: Alberto Cremonesi, Carlo Setacci, Raffaella Manetti, Gianmarco de Donato, Francesco Setacci, Guido Balestra, Ignazio Borghesi, Paolo Bianchi, Fausto Castriota
• Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology (EuroIntervention) Vol. 1 Issue 3 Pg. 289-95 (Nov 2005) ISSN: 1774-024X [Print] France
• PMID: 19758919 (Publication Type: Journal Article)