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Efficacy of chemical and/or surgical therapy against condylomata acuminata: a retrospective evaluation.

Abstract
In order to estimate treatment resistance of condylomas, standardized records of 230 males aged 17-80 years (mean 27) attending at an STD clinic were analysed retrospectively. Anal warts occurred in 38 (17%) men; in 19 (50%) intranal warts were extensive enough to require further referral to the Department of Surgery. Urinary meatal warts occurred in 30 men; 9 of them (30%) were referred to the Department of Urology. The remaining 202 (88%) men were treated in the STD clinic with simple surgery and/or home-treatment with 0.5% podophyllotoxin-ethanol twice a day for one or more 3 day sessions. After a follow-up of at least one year, 46 (23%) patients still had condylomas. However, 77 (49%) of the remaining 156 men were cured after a single therapeutic session, and after 1-4 sessions the cumulative cure rate was 77%.
AuthorsG von Krogh, A Wikström
JournalInternational journal of STD & AIDS (Int J STD AIDS) 1991 Sep-Oct Vol. 2 Issue 5 Pg. 333-8 ISSN: 0956-4624 [Print] England
PMID1958717 (Publication Type: Journal Article)
Chemical References
  • Podophyllotoxin
Topics
  • Adolescent
  • Adult
  • Aged
  • Anus Neoplasms (drug therapy, epidemiology, surgery)
  • Combined Modality Therapy
  • Condylomata Acuminata (drug therapy, epidemiology, surgery)
  • Follow-Up Studies
  • Genital Neoplasms, Male (drug therapy, epidemiology, surgery)
  • Humans
  • Male
  • Middle Aged
  • Podophyllotoxin (administration & dosage, therapeutic use)
  • Referral and Consultation (statistics & numerical data)
  • Retrospective Studies
  • Risk Factors
  • Sexual Behavior
  • Sweden (epidemiology)
  • Treatment Outcome

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