[Effect of leukotriene receptor antagonist on cough variant asthma].

Abstract

OBJECTIVE:

To study the curative effect of leukotriene receptor antagonist on cough variant asthma (CVA).

METHODS:

Sixty-four CVA patients received treatment with bricany and montelukas and 68 control patients had bricany treatment for 4 weeks. The recurrence rate was observed in the two groups during the follow-up for 6 months.

RESULTS:

The remission time of two groups were 2.5-/+3.6 and 5.3-/+3.8 days in acute phase, respectively, showing a significant difference between them (P<0.05). The recurrence rate of the two groups within 6 months were 20.09% and 40.87%, respectively, showing also significantly differences (P<0.05).

CONCLUSION:

Leukotriene receptor antagonist and bricany can effectively control CVA and significantly lower the short-term recurrence rate of CVA.

• Authors: Zhi-min He, Yu-biao Guo, Can-mao Xie
• Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University (Nan Fang Yi Ke Da Xue Xue Bao) Vol. 29 Issue 4 Pg. 694-6 (Apr 2009) ISSN: 1673-4254 [Print] China
• PMID: 19403397 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Leukotriene Antagonists
• Receptors, Leukotriene

Topics

• Adult
• Asthma (complications, drug therapy)
• Case-Control Studies
• Cough (complications, drug therapy)
• Female
• Follow-Up Studies
• Humans
• Leukotriene Antagonists (adverse effects, pharmacology, therapeutic use)
• Male
• Receptors, Leukotriene (metabolism)
• Recurrence