Abstract | INTRODUCTION: METHODS: We carried out a prospective randomized, controlled clinical trial in a regional neurosurgical center in Hong Kong. We recruited patients admitted for emergency neurosurgical operation after informed consent was obtained from next-of-kin. Eligible patients were randomized to receive an antibiotic-impregnated ventricular catheter or plain ventricular catheter Dual prophylactic antibiotic coverage was given to the patients randomized for plain ventricular catheter only. Patients who received antibiotic impregnanted catheters were not treated with systematic prophylactic antibiotics. Here we present the analysis of 110 patients, recruited over a 2-year period, to receive antibiotic-impregnanted ventricular catheters versus non-impregnated ventricular cathethers with prophylactic antibiotic coverage. FINDINGS: CONCLUSIONS:
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Authors | George K C Wong, W S Poon, Stephanie C P Ng, Margaret Ip |
Journal | Acta neurochirurgica. Supplement
(Acta Neurochir Suppl)
Vol. 102
Pg. 53-5
( 2008)
ISSN: 0065-1419 [Print] Austria |
PMID | 19388288
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Anti-Bacterial Agents
(therapeutic use)
- Antibiotic Prophylaxis
- Cerebrospinal Fluid Shunts
(adverse effects)
- Female
- Humans
- Male
- Middle Aged
- Prospective Studies
- Time Factors
- Wound Infection
(etiology, prevention & control)
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