Abstract | BACKGROUND: Early diagnosis is the main factor to improve the outcome of acute mesenteric ischemia (AMI). The goal of this study was to assess the correlation of the D-dimer test and biphasic computed tomography (CT) with mesenteric CT angiography for the diagnosis of AMI. METHODS: Selected consecutive patients with a clinical suspicion of AMI were admitted to the study. Blood samples were taken before biphasic CT with mesenteric CT angiography examination. RESULTS: The sensitivity and specificity values of biphasic CT with mesenteric CT angiography were 92.9% and 89.5%, respectively. The sensitivity and specificity of D-dimer testing for the diagnosis of AMI were 94.7% and 78.6%, respectively. D-dimer levels higher than 3.17 microg fibrinogen equivalent units/mL were more specific (P < .0001) and acted similarly to the biphasic CT with mesenteric CT angiography in the diagnosis of AMI. CONCLUSIONS: In the setting of early diagnosis of AMI, the D-dimer test may improve our ability to diagnose patients in whom we cannot use multidetector row CT with CT angiography.
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Authors | Hizir Akyildiz, Alper Akcan, Ahmet Oztürk, Erdogan Sozuer, Can Kucuk, Ibrahim Karahan |
Journal | American journal of surgery
(Am J Surg)
Vol. 197
Issue 4
Pg. 429-33
(Apr 2009)
ISSN: 1879-1883 [Electronic] United States |
PMID | 19324109
(Publication Type: Journal Article)
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Chemical References |
- Fibrin Fibrinogen Degradation Products
- fibrin fragment D
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Topics |
- Angiography
- Fibrin Fibrinogen Degradation Products
- Humans
- Mesenteric Vascular Occlusion
(diagnosis, metabolism)
- Tomography, X-Ray Computed
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