Abstract |
Gastrointestinal complications are common in patients undergoing various forms of cancer treatment, including chemotherapy, radiation therapy, and molecular-targeted therapies. Many of these complications are life-threatening and require prompt diagnosis and treatment. Complications of oncologic therapy can occur in the esophagus ( esophagitis, strictures, bacterial, viral and fungal infections), upper gastrointestinal tract ( mucositis, bleeding, nausea and vomiting), colon ( diarrhea, graft-versus-host disease, colitis and constipation), liver (drug hepatotoxicity and graft-versus-host disease), and pancreas ( pancreatitis). Treatment of the different gastrointestinal complications should be tailored to the individual patient and based on the underlying pathophysiology of the complication.
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Authors | Marta Davila, Robert S Bresalier |
Journal | Nature clinical practice. Gastroenterology & hepatology
(Nat Clin Pract Gastroenterol Hepatol)
Vol. 5
Issue 12
Pg. 682-96
(Dec 2008)
ISSN: 1743-4386 [Electronic] England |
PMID | 18941434
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Antineoplastic Agents
(adverse effects)
- Constipation
(chemically induced)
- Diarrhea
(chemically induced)
- Enterocolitis, Neutropenic
(chemically induced)
- Esophagitis
(etiology)
- Graft vs Host Disease
- Humans
- Proctitis
(etiology)
- Radiation Injuries
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