Abstract | OBJECTIVE: METHODS: One hundred and sixty-eight patients with active UC were randomly assigned to the treatment group (86 patients) and the control group (82 patients). Besides the basic treatment of oral taking salicylazosulfapyridine or mesalazine, they were treated by retention enema with predisolone plus metronidazole injection. In addition, the patients in the treatment group were treated by retention enima with GGC and orally took CGC, 0.8 g each time, thrice a day. The efficacy of treatment and the changes in the principal symptoms 2 months after treatment were evaluated. RESULTS: The total effective rate in the treatment group was 94.2% (81/86 cases), and that in the control group was 82.9% (68/82 cases), the difference between the two groups was significant (P <0. 05). The symptoms of hemafecia and abdominal pain were improved, the disease active index (DAI) was lowered after treatment in both groups (P <0.01), but the improvement of hemafecia, time of disappearance of mucous bloody stool and decrease of DAI in the treatment group were superior to those in the control group (P <0.05 or P <0.01). No adverse reaction was found in all patients. CONCLUSION:
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Authors | Hua Tan, Man-Yi Sun, Jian Yang |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 28
Issue 7
Pg. 645-7
(Jul 2008)
ISSN: 1003-5370 [Print] China |
PMID | 18822919
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Capsules
- Glucocorticoids
- Glutamine
|
Topics |
- Adolescent
- Adult
- Aged
- Capsules
- Colitis, Ulcerative
(drug therapy)
- Drug Therapy, Combination
- Enema
- Female
- Glucocorticoids
(therapeutic use)
- Glutamine
(therapeutic use)
- Humans
- Male
- Middle Aged
- Treatment Outcome
- Young Adult
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