Abstract | PURPOSE OF REVIEW: RECENT FINDINGS:
Neuropeptides and neurotrophins represent an interesting group of neuromediators actively taking place in allergic response. Mainly released at the neuronal edge or from immune and/or structural cells, neuropeptides and neurotrophins might either upregulate or downregulate inflammatory processes. These mediators contribute to ocular allergy by acting directly on cells responsible for both early and late phase reactions as well as on epithelial cells and fibroblasts, leading to either self-limiting or chronicity states. SUMMARY:
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Authors | Alessandra Micera, Alessandro Lambiase, Stefano Bonini |
Journal | Current opinion in allergy and clinical immunology
(Curr Opin Allergy Clin Immunol)
Vol. 8
Issue 5
Pg. 466-71
(Oct 2008)
ISSN: 1473-6322 [Electronic] United States |
PMID | 18769203
(Publication Type: Journal Article, Review)
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Chemical References |
- Nerve Growth Factors
- Neuropeptides
- Neurotransmitter Agents
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Topics |
- Conjunctivitis, Allergic
(immunology, physiopathology)
- Eye Diseases
(immunology, physiopathology)
- Humans
- Hypersensitivity
(immunology, physiopathology)
- Nerve Growth Factors
(immunology, metabolism)
- Neurogenic Inflammation
(immunology, physiopathology)
- Neuropeptides
(immunology, metabolism)
- Neurotransmitter Agents
(immunology, metabolism)
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