Abstract | BACKGROUND:
Disulfiram has demonstrated efficacy in six randomized clinical trials for the treatment of cocaine dependence, but is rarely used in clinical settings because of safety concerns. OBJECTIVE: METHODS: We located Phase I and II randomized trials that discussed the safety of disulfiram. RESULTS/CONCLUSIONS:
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Authors | Robert Malcolm, M Foster Olive, William Lechner |
Journal | Expert opinion on drug safety
(Expert Opin Drug Saf)
Vol. 7
Issue 4
Pg. 459-72
(Jul 2008)
ISSN: 1744-764X [Electronic] England |
PMID | 18613809
(Publication Type: Journal Article, Review)
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Chemical References |
- Alcohol Deterrents
- Disulfiram
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Topics |
- Alcohol Deterrents
(administration & dosage, adverse effects, therapeutic use)
- Alcoholism
(drug therapy)
- Clinical Trials, Phase I as Topic
- Clinical Trials, Phase II as Topic
- Cocaine-Related Disorders
(drug therapy)
- Disulfiram
(administration & dosage, adverse effects, therapeutic use)
- Dose-Response Relationship, Drug
- Drug Interactions
- Humans
- Randomized Controlled Trials as Topic
- Risk Factors
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