Abstract | BACKGROUND AND OBJECTIVE: MATERIAL AND METHODS: RESULTS: Serum resistin levels and total leukocyte counts in subjects with periodontitis were higher than in control subjects. No significant differences were observed in adiponectin, IL-6 and TNF-alpha levels between subjects with and without periodontitis. Logistic regression analysis showed that periodontitis with at least one tooth that displayed a probing pocket depth of > or =6 mm was significantly associated with higher serum resistin levels (odds ratio, 2.0; 95% confidence interval, 1.0-4.0). When excluding periodontitis subjects with < or =10% of bleeding on probing and excluding control subjects with >10% bleeding on probing, differences between groups and odds ratio increased. Serum adiponectin tended to decrease in patients with periodontitis, albeit not significantly. CONCLUSION: Increased serum resistin levels were significantly associated with periodontal condition, especially when considering bleeding on probing, in elderly Japanese people. There was also a trend, though non-significant, toward decreased levels of adiponectin in subjects with periodontitis.
|
Authors | R Furugen, H Hayashida, N Yamaguchi, A Yoshihara, H Ogawa, H Miyazaki, T Saito |
Journal | Journal of periodontal research
(J Periodontal Res)
Vol. 43
Issue 5
Pg. 556-62
(Oct 2008)
ISSN: 1600-0765 [Electronic] United States |
PMID | 18565135
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Adiponectin
(blood)
- Aged
- Case-Control Studies
- Chronic Periodontitis
(blood, pathology)
- Female
- Humans
- Leukocyte Count
- Logistic Models
- Male
- Resistin
(blood)
- Sex Factors
|