Narrowband UVB (311 nm, TL01) phototherapy for pityriasis lichenoides.

Abstract

BACKGROUND/PURPOSE:

Narrowband (NB) UVB (NB-UVB) phototherapy has recently demonstrated high levels of efficacy and tolerability in a variety of skin diseases. The purpose of the present study was to assess the efficacy of NB-UVB phototherapy in the management of pityriasis lichenoides (PL).

METHODS:

The therapeutic response in 31 PL patients (23 pityriasis lichenoides et varioliformis acuta; PLEVA, eight pityriasis lichenoides chronica; PLC) treated with NB-UVB phototherapy between 2000 and 2007 was assessed.

RESULTS:

NB-UVB treatment led to a complete response (CR) in 15 out of 23 PLEVA patients (65.2%) with a mean cumulative dose of 23 J/cm(2) after a mean number of 43.4 exposures and a partial response (PR) in eight patients (34.8%) with a cumulative dose of 15.6 J/cm(2) after a mean number of 32.3 exposures. NB-UVB treatment led to CR in seven out of eight PLC patients (87.5%) with a mean cumulative dose of 18.4 J/cm(2) after a mean number of 45.8 exposures and PR in one patient (12.5%) with a cumulative dose of 9.1 J/cm(2) after a mean number of 19 exposures. Relapses occurred in four PL patients within a mean time period of 6 months.

CONCLUSION:

NB-UVB therapy is an effective, safe and practical alternative treatment modality for the management of PLEVA and PLC.

• Authors: Kenan Aydogan, Hayriye Saricaoglu, Hakan Turan
• Journal: Photodermatology, photoimmunology & photomedicine (Photodermatol Photoimmunol Photomed) Vol. 24 Issue 3 Pg. 128-33 (Jun 2008) ISSN: 1600-0781 [Electronic] England
• PMID: 18477131 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Aged
• Child
• Female
• Humans
• Male
• Middle Aged
• Pityriasis Lichenoides (radiotherapy)
• Radiation Dosage
• Recurrence
• Remission Induction
• Retrospective Studies
• Treatment Outcome
• Ultraviolet Therapy (methods)