[Anticardiolipin antibodies and primary antiphospholipid syndrome of the central nervous system: report of 10 clinical cases].

Abstract

An association between anti-phospholipid antibodies and different disorders of the central nervous system has been described recently. We used an ELISA technique and detected anti-cardiolipin antibodies of the IgG or IgM variety in a series of 10 patients: 4 had occlusive stroke, 2 brain hemorrhage, 2 chorea, 1 a Sneddon syndrome and 1 vascular cephalea. The diagnosis of primary anti-phospholipid syndrome was suggested after ruling out systemic lupus in all patients.

• Authors: J L Córdova, O Neira, P Abumohor, S Palma, F Vergara, L Guzmán
• Journal: Revista medica de Chile (Rev Med Chil) Vol. 119 Issue 7 Pg. 765-71 (Jul 1991) ISSN: 0034-9887 [Print] Chile
• Vernacular Title: Anticuerpos anticardiolipinas y síndrome antifosfolípidos primario del sistema nervioso central: comunicación de 10 casos clínicos.
• PMID: 1844751 (Publication Type: Case Reports, English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Anticardiolipin
• Immunoglobulin G
• Immunoglobulin M

Topics

• Adult
• Aged
• Antibodies, Anticardiolipin (analysis, metabolism)
• Antiphospholipid Syndrome (complications, diagnosis, immunology)
• Cerebral Infarction (complications, diagnosis, immunology)
• Enzyme-Linked Immunosorbent Assay
• Female
• Humans
• Immunoglobulin G (blood)
• Immunoglobulin M (blood)
• Male
• Middle Aged
• Risk Factors
• Tomography, X-Ray Computed