HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Quantitative ultrasound methods to assess bone mineral status in children: technical characteristics, performance, and clinical application.

Abstract
Measurement of bone mineral status may be a useful tool in identifying the children who could be exposed to an increased risk of osteoporosis in adulthood. Dual energy x-ray absorptiometry and peripheral quantitative computed tomography may be used to this purpose, but the exposure to ionizing radiation is a limiting factor for preventive studies in large populations of children. In the last years, quantitative ultrasound (QUS) methods have been developed to assess bone mineral status in some peripheral skeletal sites such as calcaneus, phalanges of the hand, and tibia. QUS techniques are safe, easy to use, radiation-free, and devices are portable, so that they are particularly indicated to assess bone mineral status in children. This review will concentrate on the main methodological principles of ultrasounds and the QUS variables derived from their application to bone tissue, technical differences and performance of QUS methods, factors influencing QUS measurements, normative data and results obtained in children with disturbances of growth or affected by disorders of bone and mineral metabolism, including the assessment of fracture risk, and comparison among QUS, dual energy x-ray absorptiometry, and peripheral quantitative computed tomography methods.
AuthorsGiampiero I Baroncelli
JournalPediatric research (Pediatr Res) Vol. 63 Issue 3 Pg. 220-8 (Mar 2008) ISSN: 0031-3998 [Print] United States
PMID18287958 (Publication Type: Journal Article, Review)
Topics
  • Absorptiometry, Photon
  • Bone Density
  • Bone Diseases, Metabolic (complications, diagnostic imaging, physiopathology)
  • Bone and Bones (diagnostic imaging)
  • Child
  • Diagnostic Imaging (adverse effects, instrumentation, methods)
  • Equipment Design
  • Fractures, Bone (diagnostic imaging, etiology, physiopathology)
  • Humans
  • Reference Values
  • Reproducibility of Results
  • Risk Assessment
  • Risk Factors
  • Tomography, X-Ray Computed
  • Ultrasonography

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: