[Two cases of colon cancer after resection of recurrence at peritoneal dissemination were for long-term survival with adjuvant chemotherapy].

Abstract

Generally the peritoneal dissemination of digestive cancer was difficult to control. The symptom of dissemination will decrease quality of life (QOL) for these patients. The diagnosis for the range of dissemination was difficult. Therefore, the decision of the treatment was wavered between an operation and chemotherapy. The effect of chemotherapy was controversial so the cure was inconsistent. We experienced with two recurrent colon cancer patients who underwent resection of peritoneal dissemination and adjuvant chemotherapy. Case 1 was a 62-year-old man. He was operated for left colectomy against descending colon cancer with perforation. After two years, the recurrence of peritoneal dissemination and short bowel obstruction appeared. He was performed short bowel resection and FOLFIRI chemotherapy after surgery. Case 2 was a 72-year-old woman. She was operated on sigmidectomy against sigmoid colon cancer. After three years, the recurrence of peritoneal dissemination at the anastomotic lesion appeared. She was performed low anterior resection (LAR) and S-1 chemotherapy after surgery. But after 3.5 years, the peritoneal dissemination at the anastomotic lesion appeared once more. We decided to have LAR operation and FOLFOX 4 chemotherapy. Both cases maintained a good QOL for a long time. The operation against peritoneal dissemination was one of the good treatments if the range of peritoneal dissemination was clearly restricted.

• Authors: Katsunori Ami, Masahiro Taira, Hideaki Ganno, Norihito Kawasaki, Masahide Ohbu, Akira Fukuda, Takeshi Nagahama, Tetsushi Ito, Masayuki Ando
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 34 Issue 12 Pg. 2044-6 (Nov 2007) ISSN: 0385-0684 [Print] Japan
• PMID: 18219893 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Aged
• Chemotherapy, Adjuvant
• Female
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local (drug therapy, secondary, surgery)
• Peritoneal Neoplasms (drug therapy, secondary, surgery)
• Rectal Neoplasms (drug therapy, pathology, surgery)
• Sigmoid Neoplasms (drug therapy, pathology, surgery)