[Intrauterine treatment of incomplete fetal heart block in a mother with Sjögren syndrome].

Abstract

BACKGROUND:

Isolated fetal heart block is considered as an immunological disorder in the majority of cases. Mothers of affected fetuses often suffer from connective tissue disease (Sjögren syndrome or Lupus erythematodes). All of them test positive for anti-SS-A (anti Ro) and/or anti-SS-B (anti La) antibodies. Once established, third-degree congenital heart block is permanent and often requires a pacemaker.

CASE:

We report on a pregnancy in a mother with Sjögren syndrome which was complicated by the development of incomplete fetal heart block, diagnosed by pulsed wave Doppler echocardiography. We started oral dexamethasone treatment to reduce immune-mediated fetal cardiac damage and to prevent complications like hydrops fetalis.

CONCLUSION:

Detection of isolated fetal heart block is possible with pulsed Doppler sonography, but there are no clear recommendations for treatment.

• Authors: A Hagen, M Albig, L Schmitz, H Hopp, M Entezami
• Journal: Ultraschall in der Medizin (Stuttgart, Germany : 1980) (Ultraschall Med) Vol. 29 Suppl 5 Pg. 268-70 (Dec 2008) ISSN: 1438-8782 [Electronic] Germany
• Vernacular Title: Intrauterine Therapie eines inkompletten AV-Blocks bei einer Mutter mit Sjögren-Syndrom.
• PMID: 18008217 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Echocardiography, Doppler (methods)
• Female
• Fetal Heart (diagnostic imaging, physiopathology)
• Heart Block (diagnostic imaging, embryology, therapy)
• Heart Conduction System (diagnostic imaging, embryology)
• Humans
• Pregnancy
• Pregnancy Complications (diagnostic imaging)
• Sjogren's Syndrome (diagnostic imaging)
• Systole