Abstract | BACKGROUND: METHODS: Twenty-three adult male patients with moderate-to-severe OSAS but without obesity, coronary heart disease and diabetes were recruited. Their blood samples were collected and morning mean arterial pressure (MAP) was measured before CPAP treatment and on day 3, 7, 14 of CPAP treatment respectively. The serum adiponectin concentration was tested with radioimmunoassay. RESULTS: Compared with the serum adiponectin level before CPAP treatment, no significant change was found in OSAS patients on day 3 and day 7 of CPAP treatment (P > 0.05). It was not until day 14 of CPAP treatment did a significant elevation in serum adiponectin level occur (P < 0.01). Meanwhile, the MAP showed no statistically significant difference among its levels before CPAP, on day 3 and day 7 of CPAP treatment (P > 0.05). However, on day 14 of CPAP treatment, a significantly lower MAP than that obtained before treatment was observed (P < 0.05). CONCLUSIONS:
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Authors | Xi-long Zhang, Kai-sheng Yin, Chong Li, En-zhi Jia, Yan-qun Li, Zhao-fang Gao |
Journal | Chinese medical journal
(Chin Med J (Engl))
Vol. 120
Issue 17
Pg. 1477-81
(Sep 05 2007)
ISSN: 0366-6999 [Print] China |
PMID | 17908452
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adiponectin
(blood)
- Adult
- Aged
- Blood Pressure
- Continuous Positive Airway Pressure
- Humans
- Male
- Middle Aged
- Sleep Apnea, Obstructive
(blood, complications, physiopathology, therapy)
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