A case of anaphylactic reaction to praziquantel treatment.

Abstract

A 35-year-old Chinese man was administered praziquantel for clonorchiasis, and 30 minutes later he experienced a sudden onset of itching urticaria over his entire body with dyspnea, palpitation, and dizziness. The patient had no recent medication history except for the praziquantel. He was diagnosed as having an anaphylactic reaction with skin eruptions induced by praziquantel. His symptoms subsided after a stomach wash and the administration of anti-anaphylactic medication in emergency department of a regional hospital in the People's Republic of China. The immediate type of hypersensitive reaction to praziquantel is plausible, and this reaction should be considered for praziquantel therapy.

• Authors: Chenghua Shen, Min-Ho Choi, Young Mee Bae, Gui Yu, Shuhua Wang, Sung-Tae Hong
• Journal: The American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 76 Issue 3 Pg. 603-5 (Mar 2007) ISSN: 0002-9637 [Print] United States
• PMID: 17360893 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anthelmintics
• Praziquantel

Topics

• Adult
• Anaphylaxis (chemically induced)
• Anthelmintics (adverse effects)
• Clonorchiasis (drug therapy)
• Drug Eruptions (etiology)
• Humans
• Male
• Praziquantel (adverse effects)