[Endoscopic endonasal transsphenoidal approach for pituitary adenomas].

Abstract

OBJECTIVE:

To assess the clinical curative effect of the endonasal transsphenoidal approach for removing pituitary adenoma (PA) under neuroendoscope-assisted.

METHODS:

There were 215 patients who had undergone neuroendoscopic transsphenoidal surgery. Each patient received CT or MRI examination which showed the size and surrounding structural of tumor.

RESULTS:

Among the 215 patients, 190 cases (88.4%) had total removal, 17 cases (7.9%) achieved subtotal removal and the remaining 8 cases (3.7%) with fibrous tumor was carried out partial removal. Two patients (0.9%) died after operation. Postoperative follow-up period was 1 to 10 months (the average was 3.5 months). In 182 patients, 150 cases (90.9%) got vision recovered rapidly compared with their preoperative symptoms, such as diminished acuities and visual field defects, and 15 cases (9.1%) had gotten improvements to some extend among 165 who diagnosed as pituitary macroadenoma (PMaA); There were 17 patients who diagnosed as microadenoma (PMiA) showed that the pituitary dyshormonism recovered gradually.

CONCLUSIONS:

The endonasal transsphenoidal surgery under the neuroendoscope-assisted appears to be a safe, effective and micro-invasive method for PA.

• Authors: Xiang Zhang, Zhou Fei, Jian-ning Zhang, Wei-ping Liu, Luo-an Fu, Shao-jun Song, Wei Zhang, Xiao-sheng He, Xiao-fan Jiang, Wei-dong Cao
• Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] (Zhonghua Wai Ke Za Zhi) Vol. 44 Issue 22 Pg. 1551-4 (Nov 15 2006) ISSN: 0529-5815 [Print] China
• PMID: 17359662 (Publication Type: English Abstract, Journal Article)

Topics

• Adenoma (surgery)
• Adolescent
• Adult
• Aged
• Female
• Follow-Up Studies
• Humans
• Hypophysectomy (methods)
• Male
• Middle Aged
• Nasal Cavity (surgery)
• Neuroendoscopy
• Pituitary Neoplasms (surgery)
• Retrospective Studies
• Sphenoid Sinus (surgery)
• Treatment Outcome