HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection.

AbstractOBJECTIVE:
The aim of this study was to compare the topical anesthetic effect of 20% benzocaine gel with 2.5% lidocaine/2.5% prilocaine (L/P) cream and gel on the pain experienced during palatal anesthetic infiltration.
STUDY DESIGN:
Two groups were studied, each containing 20 subjects. Two types of L/P mixtures were tested, an anesthetic cream (EMLA) and a thermosetting gel (Oraqix), and benzocaine was used as control. The topical agents were applied on the palatal mucosa at the canine region. A needle prick was given on each side every 2 minutes during a period of 10 minutes. The subjects recorded their findings using verbal and VAS scales.
RESULTS:
Pain scores were significantly less (P < .05) with EMLA and Oraqix than with benzocaine.
CONCLUSION:
Topical application of EMLA and Oraqix before palatal anesthetic infiltration is associated with less pain than with benzocaine gel.
AuthorsManal Abu Al-Melh, Lars Andersson
JournalOral surgery, oral medicine, oral pathology, oral radiology, and endodontics (Oral Surg Oral Med Oral Pathol Oral Radiol Endod) Vol. 103 Issue 5 Pg. e16-20 (May 2007) ISSN: 1528-395X [Electronic] United States
PMID17331753 (Publication Type: Comparative Study, Controlled Clinical Trial, Journal Article)
Chemical References
  • Anesthetics, Local
  • Gels
  • Lidocaine, Prilocaine Drug Combination
  • Ointments
  • Prilocaine
  • Lidocaine
  • Benzocaine
Topics
  • Adult
  • Anesthesia, Dental (methods)
  • Anesthesia, Local (methods)
  • Anesthetics, Local (administration & dosage)
  • Benzocaine (administration & dosage)
  • Gels
  • Humans
  • Injections (adverse effects)
  • Lidocaine (administration & dosage)
  • Lidocaine, Prilocaine Drug Combination
  • Mouth Mucosa
  • Needles (adverse effects)
  • Ointments
  • Pain (etiology, prevention & control)
  • Pain Measurement
  • Palate, Hard
  • Prilocaine (administration & dosage)
  • Single-Blind Method

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: