Abstract | PURPOSE: DESIGN: Interventional case series. METHODS: Retrospective chart and literature review. RESULTS: The first patient had neonatally acquired herpetic keratitis and developed ARN at age 21. Polymerase chain reaction of a vitreous biopsy detected HSV type-2 (HSV-2). The second patient was clinically diagnosed with ARN contralateral to varicella zoster keratitis. A detailed literature search located seven prior case reports with a von Szily reaction. These resembled our two cases except none had HSV-2 or years of latency from keratitis to retinitis. CONCLUSIONS: Clinicians need to be cognizant of the von Szily reaction.
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Authors | Lynnelle K Smith, Paul A Kurz, David J Wilson, Christina J Flaxel, James T Rosenbaum |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 143
Issue 3
Pg. 536-8
(Mar 2007)
ISSN: 0002-9394 [Print] United States |
PMID | 17317412
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antiviral Agents
- Glucocorticoids
- Timolol
- Cyclopentolate
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Topics |
- Adult
- Antiviral Agents
(therapeutic use)
- Cyclopentolate
(therapeutic use)
- Drug Therapy, Combination
- Female
- Glucocorticoids
(therapeutic use)
- Herpesvirus 2, Human
(genetics, isolation & purification)
- Herpesvirus 3, Human
(genetics, isolation & purification)
- Humans
- Keratitis, Herpetic
(complications, diagnosis, drug therapy)
- Male
- Polymerase Chain Reaction
- Retinal Necrosis Syndrome, Acute
(diagnosis, drug therapy, etiology)
- Retrospective Studies
- Timolol
(therapeutic use)
- Vitreous Body
(virology)
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