Miliarial gout (a new entity).

Abstract

BACKGROUND:

Tophaceous gout typically presents as a subcutaneous, nodular collection of monosodium urate crystals sharply circumscribed from surrounding tissues. Although intradermal cutaneous manifestations of gout have been described, no reported cases of miliarial gout remain.

OBJECTIVE:

We describe the first known presentation of miliarial gout and list other uncommon cutaneous manifestations of gouty tophi. The treatment of miliarial gout is discussed, as well as risk factors predisposing an individual to the development of intradermal tophi.

RESULTS:

Miliarial gout is an intradermal phenomenon consisting of multiple tiny papules containing material of a white to cream color scattered on an erythematous base that responds to allopurinol administration. Risk factors predisposing an individual to the development of intradermal gout include renal insufficiency, hypertension, chronic diuretic therapy, long duration of disease, and lack of consistent use of urate-lowering therapy.

CONCLUSION:

Miliarial gout is a unique intradermal manifestation of tophaceous gout.

• Authors: Rahul Shukla, Ronald B Vender, Ayman Alhabeeb, Samih Salama, Frank Murphy
• Journal: Journal of cutaneous medicine and surgery (J Cutan Med Surg) 2007 Jan-Feb Vol. 11 Issue 1 Pg. 31-4 ISSN: 1203-4754 [Print] United States
• PMID: 17274936 (Publication Type: Case Reports, Journal Article)

Chemical References

• Gout Suppressants
• Allopurinol
• Colchicine

Topics

• Aged
• Allopurinol (therapeutic use)
• Colchicine (therapeutic use)
• Gout (diagnosis, drug therapy, pathology)
• Gout Suppressants (therapeutic use)
• Humans
• Male