Abstract | PURPOSE: METHODS: Eighty-eight patients scheduled for elective CABG were studied. After the induction of anesthesia, a fiberoptic oximetry oxygen saturation catheter was inserted into the right jugular bulb for the continuous monitoring of jugular venous oxygen hemoglobin saturation (SjvO(2)). The hemodynamic parameters and arterial and jugular venous blood gases were measured during cardiopulmonary bypass (CPB). All patients underwent a battery of neurological and neuropsychological tests one day before the operation and at 6 months after the operation. RESULTS: The incidence of a cognitive decline at 6 months was 24/88 (27.3%). Greater age (P = 0.04), the presence of renal failure (P < 0.001), and diabetes mellitus (P < 0.001) were more frequent in the patients with postoperative cognitive dysfunction at 6 months after the operation than in patients without cognitive dysfunction. Age (odds ratio [OR], 1.4; 95% confidence interval [CI], 1.0-1.7; P = 0.04), diabetes mellitus (OR, 1.8; 95% CI, 1.2-2.4; P < 0.01), and presence of renal failure (OR, 2.8; 95% CI, 2.4-4.3; P < 0.01) were associated with cognitive impairment at 6 months postoperatively. However, there was no relationship between the presence of atherosclerosis in the ascending aorta and postoperative cognitive dysfunction after CABG surgery. CONCLUSIONS:
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Authors | Yuji Kadoi, Fumio Goto |
Journal | Surgery today
(Surg Today)
Vol. 36
Issue 12
Pg. 1053-7
( 2006)
ISSN: 0941-1291 [Print] Japan |
PMID | 17123132
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Age Factors
- Aged
- Cognition Disorders
(diagnosis, epidemiology, etiology)
- Coronary Artery Bypass
(adverse effects)
- Coronary Disease
(complications, surgery)
- Diabetes Mellitus, Type 2
(complications)
- Female
- Follow-Up Studies
- Humans
- Incidence
- Kidney Failure, Chronic
(complications)
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Odds Ratio
- Oximetry
- Postoperative Complications
- Prognosis
- Retrospective Studies
- Risk Factors
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