Abstract | BACKGROUND: METHODS: A retrospective review was performed on 185 patients who had undergone an extracardiac Fontan operation between 1996 and 2005. RESULTS: Sixty-two of the patients had heterotaxy syndrome (33.5%). Forty-one had right isomerism and 21 had left isomerism. Heterotaxy syndrome was commonly associated with a morphologic right ventricle (59.7%), a common atrioventricular valve (72.6%), an interrupted inferior vena cava (25.8%), a separate hepatic vein (30.6%), and extracardiac pulmonary venous drainage (16.1%). The hospital mortality rate was higher in the heterotaxy syndrome than nonheterotaxy (4.8% vs 2.4%; p = 0.05). Eight-year survivals were 91.9 +/- 3.2% in the nonheterotaxy group and 89.3 +/- 4.2 % in the heterotaxy group (p = 0.39). At 8 years, freedom from reoperation was 90.2 +/- 3.2% in the nonheterotaxy group and 78.5 +/- 6.2% in the heterotaxy group (p = 0.15). The outcomes (other than those of arrhythmia) were no different between the two groups. The incidences of early and late postoperative arrhythmia were 29.0% and 25.4%, respectively, in heterotaxy patients, and 15.4% and 10.8% in nonheterotaxy patients (p < 0.05). Bradyarrhythmia was found to be more common. During follow-up, atrioventricular valve regurgitation of more than mild was more common in heterotaxy patients (33.9% vs 18.9%; p = 0.05). CONCLUSIONS: Midterm outcomes after an extracardiac Fontan operation in heterotaxy and nonheterotaxy patients are similar, except arrhythmia and atrioventricular valve regurgitation.
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Authors | Soo-Jin Kim, Woong-Han Kim, Hong Gook Lim, Chang-Ha Lee, Jae Young Lee |
Journal | The Annals of thoracic surgery
(Ann Thorac Surg)
Vol. 82
Issue 4
Pg. 1245-51
(Oct 2006)
ISSN: 1552-6259 [Electronic] Netherlands |
PMID | 16996916
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Arrhythmias, Cardiac
(etiology)
- Child
- Child, Preschool
- Female
- Fontan Procedure
(adverse effects)
- Heart Defects, Congenital
(mortality, surgery)
- Humans
- Infant
- Male
- Prognosis
- Reoperation
- Retrospective Studies
- Survival Analysis
- Syndrome
- Treatment Outcome
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