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In vitro activity of ceftobiprole against aerobic and anaerobic strains isolated from diabetic foot infections.

Abstract
Against 443 aerobic and anaerobic bacteria isolated from diabetic foot infections, ceftobiprole MICs (microg/ml) at which 90% of the isolates tested were inhibited were as follows: methicillin-resistant Staphylococcus aureus, 1; methicillin-susceptible S. aureus and Staphylococcus lugdunensis, 0.5; Anaerococcus prevotii, 0.125; Finegoldia magna, 0.5; Peptoniphilus asaccharolyticus, 1; Peptostreptococcus anaerobius, 4; Escherichia coli and Enterobacter species, 0.125; Klebsiella species, 2; and Pseudomonas aeruginosa, 8.
AuthorsEllie J C Goldstein, Diane M Citron, C Vreni Merriam, Yumi A Warren, Kerin L Tyrrell, Helen T Fernandez
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 50 Issue 11 Pg. 3959-62 (Nov 2006) ISSN: 0066-4804 [Print] United States
PMID16982780 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Anti-Bacterial Agents
  • Cephalosporins
  • ceftobiprole
Topics
  • Anti-Bacterial Agents (pharmacology)
  • Bacteria, Aerobic (drug effects)
  • Bacteria, Anaerobic (drug effects)
  • Cephalosporins (pharmacology)
  • Diabetic Foot (microbiology)
  • Drug Resistance, Bacterial
  • Humans
  • Microbial Sensitivity Tests

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