HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Conservative treatment of spontaneous spinal epidural hematoma associated with oral anticoagulant therapy in a child.

AbstractOBJECTIVE:
Spontaneous spinal epidural hematoma (SSEH) is rare in the pediatric population. This case report reviews the indications and strategies for nonoperative management in selected patients.
METHODS:
An eight-year-old boy presented with back pain. There was no antecedent trauma, but the patient was anticoagulated for a mechanical heart valve. MRI revealed an epidural mass from T12 to L2 consistent with SSEH. The absence of focal neurologic deficits, combined with the high stroke risk with anticoagulation reversal, prompted a nonoperative approach. Clinical symptoms resolved over several weeks while maintaining therapeutic anticoagulation. Follow-up MRI demonstrated resolution of the hematoma.
CONCLUSION:
SSEH can present in the setting of poorly controlled therapeutic anticoagulation in the pediatric population. This case supports the premise that patients who present with SSEH without focal neurologic deficit can be successfully managed while maintaining therapeutic levels of anticoagulation. Close follow-up with frequent neurologic examinations, imaging and monitoring of the prothrombin time is mandatory.
AuthorsJignesh Tailor, Ian F Dunn, Edward Smith
JournalChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (Childs Nerv Syst) Vol. 22 Issue 12 Pg. 1643-5 (Dec 2006) ISSN: 0256-7040 [Print] Germany
PMID16977486 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anticoagulants
  • Warfarin
Topics
  • Administration, Oral
  • Anticoagulants (administration & dosage, adverse effects)
  • Child
  • Heart Valve Prosthesis
  • Hematoma, Epidural, Spinal (chemically induced, pathology, therapy)
  • Humans
  • Magnetic Resonance Angiography
  • Male
  • Warfarin (administration & dosage, adverse effects)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: