Abstract | OBJECTIVE: METHODS: RESULTS: Twenty-one of 782 studied patients (2.7%) acquired 26 microbiologically documented nosocomial infections after off-pump coronary artery bypass grafting. Eight of 782 studied patients had pneumonia (1.02%), 7 of 782 (0.90%) had bacteremia, 4 of 782 (0.51%) had superficial wound infection at the sternotomy site, 4 of 782 (0.51%) had urinary tract infection, 2 of 782 (0.26%) had mediastinitis, and 1 of 782 (0.13%) had pressure sore infection. Twenty-one infections were monomicrobial, whereas 5 were polymicrobial. All polymicrobial infections were wound infections. There was a statistically significant difference in mortality between patients with and without nosocomial infection (23.8% vs 1.2%, P < .001). Clinical response of the infection to the treatment administered was observed in 21 of 26 episodes (80.8%) in 21 patients. A backward stepwise multivariable logistic regression model showed that independent risk factors (P < .05) associated with development of microbiologically documented nosocomial infection were arterial hypertension, previous vascular surgery, urgent operation, postoperative atrial fibrillation, number of inotropes used during and after operation, transfusion of fresh-frozen plasma during the intensive care unit stay, and intensive care unit stay until development of infection. CONCLUSION:
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Authors | Matthew E Falagas, Evangelos S Rosmarakis, Konstantinos Rellos, Argyris Michalopoulos, George Samonis, Sotirios N Prapas |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 132
Issue 3
Pg. 481-90
(Sep 2006)
ISSN: 1097-685X [Electronic] United States |
PMID | 16935099
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Coronary Artery Bypass, Off-Pump
(adverse effects)
- Cross Infection
(complications, epidemiology, etiology, microbiology)
- Female
- Humans
- Male
- Middle Aged
- Prospective Studies
- Risk Factors
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