Hemocoagulation was studied in 116 patients with
prostatic adenoma, stage II, before and 1, 4-7, 8-10 and 11-15 days after surgical intervention. Out of 77 patients exposed to routine adenomectomy, 55 persons were treated 12-14 days prior the surgery with therapeutic dosages of a
vitamin A, E, C, P complex. After the operation they were given
nicotinic acid in presence of the double load of
vitamins A and E. Out of 39 persons exposed to urgent adenomectomy 19 patients were administered the double dosages of the same
vitamins before the operation. The rest of the both groups were postsurgically given
acetylsalicylic acid instead of
vitamins. It was stated that the aforementioned
vitamin therapy significantly decreased postsurgical
blood coagulation disorders (in those who were prepared for the operation beforehand it happened before adenomectomy), improved the
clinical course and outcomes of the postsurgical period. Presurgical investigations reveal an accelerated intravascular coagulation and mild manifestations of the
DIC syndrome in patients with
prostatic adenoma. After the operation the syndrome manifestations increase but rarely develop into stages II and III that are usually accompanied by
consumption coagulopathy. To follow the syndrome progression one could use only 5 out of 13 tests defined by the authors: activated time of recalcification,
prothrombin index, fibrinolytic activity, products of
fibrin degradation and an
ethanol test.