A novel double-antigen sandwich enzyme-linked immunosorbent assay for Measurement of Antibodies against rabies virus.

Abstract

A novel double-antigen sandwich enzyme-linked immunosorbent assay (ELISA) was developed to measure rabies antibodies in dogs. In contrast to the 4 days required for detecting rabies antibody with conventional rabies antibody virus neutralization assays, this ELISA can be completed in hours, without using live virus, in routine laboratories.

• Authors: Li-Min Yang, Liang-Zhen Zhao, Rong-Liang Hu, Zhen-Sheng Shi, Wen-Jun Liu
• Journal: Clinical and vaccine immunology : CVI (Clin Vaccine Immunol) Vol. 13 Issue 8 Pg. 966-8 (Aug 2006) ISSN: 1556-6811 [Print] United States
• PMID: 16893999 (Publication Type: Comparative Study, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Viral
• Antigens, Viral
• Recombinant Proteins

Topics

• Amino Acid Sequence
• Animals
• Antibodies, Viral (blood)
• Antigens, Viral (classification, genetics, immunology)
• Dogs
• Enzyme-Linked Immunosorbent Assay (methods)
• Molecular Sequence Data
• Rabies (blood, immunology)
• Rabies virus (immunology)
• Recombinant Proteins (genetics, immunology)
• Sensitivity and Specificity
• Time Factors