Abstract | BACKGROUND AND OBJECTIVES:
IgA deficient patients are at risk of severe anaphylactic reaction on being transfused blood and blood products, and its prevalence varies in different parts of the world. No data are available from India. We did a blood donor survey to look for prevalence of IgA deficiency in north India. METHODS: RESULTS: Of the 3818 blood donors screened, 3640 (95.3%) were males with a mean age of 31.2 yr. No donor was found to have complete IgA deficiency; however, 257 (6.7%) had partial IgA deficiency. INTERPRETATION AND CONCLUSION:
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Authors | Shelly Chandran, Dheeraj Khetan, Rajendra Chaudhary, Ramnath Misra, Amita Aggarwal |
Journal | The Indian journal of medical research
(Indian J Med Res)
Vol. 123
Issue 5
Pg. 653-6
(May 2006)
ISSN: 0971-5916 [Print] India |
PMID | 16873907
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Autoantibodies
- Immunoglobulin A
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Topics |
- Adolescent
- Adult
- Anaphylaxis
(etiology)
- Autoantibodies
(blood)
- Blood Donors
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- IgA Deficiency
(diagnosis, epidemiology, immunology)
- Immunoglobulin A
(blood, immunology)
- India
(epidemiology)
- Male
- Middle Aged
- Transfusion Reaction
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