Abstract | BACKGROUND: METHODS: A total of 196 children--93% of patients surviving kidney, liver and heart transplantation in Finland--participated in a cross-sectional survey. All children underwent a detailed clinical examination and filled out a questionnaire on musculoskeletal symptoms. Radiographs were taken in case of joint pain or abnormal clinical findings. In addition, magnetic resonance imaging (MRI) from the hips was taken on a random basis from 34 adult patients transplanted as a child. The mean follow-up time of all patients after transplantation was 9.2 years (range, 2.4 to 20.5 years). RESULTS: Twenty-eight (14%) patients reported prolonged joint or limb pain without previous trauma. Specific etiology for the limb pain was not found in 10 (5.1%) patients. Osteonecrosis seen in radiographs or MRI was noted in seven (3.6%) patients, of which three had received kidney, three liver, and one heart graft. Femoral head was affected in five patients, as well as talus bilaterally in one patient and lateral femoral condyle in one patient. All patients were older than 12 years at the time of diagnosis of the osteonecrosis. MRI of the hips of 34 randomly selected patients showed only one asymptomatic necrosis of the femoral head. CONCLUSIONS:
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Authors | Ilkka Helenius, Hannu Jalanko, Ville Remes, Pekka Tervahartiala, Sari Salminen, Heikki Sairanen, Christer Holmberg, Miia Helenius, Yrjänä Nietosvaara, Jari Peltonen |
Journal | Transplantation
(Transplantation)
Vol. 81
Issue 12
Pg. 1621-7
(Jun 27 2006)
ISSN: 0041-1337 [Print] United States |
PMID | 16794525
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Child
- Child, Preschool
- Female
- Follow-Up Studies
- Heart Transplantation
- Hip Joint
(pathology)
- Humans
- Kidney Transplantation
- Liver Transplantation
- Magnetic Resonance Imaging
- Male
- Osteonecrosis
(diagnosis, diagnostic imaging, pathology)
- Radiography
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