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Elevated human tissue kallikrein levels in the stratum corneum and serum of peeling skin syndrome-type B patients suggests an over-desquamation of corneocytes.

AuthorsNahoko Komatsu, Yasushi Suga, Kiyofumi Saijoh, Amber C Liu, Saba Khan, Yuki Mizuno, Shigaku Ikeda, Hua-Kang Wu, Arumugam Jayakumar, Gary L Clayman, Fumiaki Shirasaki, Kazuhiko Takehara, Eleftherios P Diamandis
JournalThe Journal of investigative dermatology (J Invest Dermatol) Vol. 126 Issue 10 Pg. 2338-42 (Oct 2006) ISSN: 0022-202X [Print] United States
PMID16778802 (Publication Type: Letter, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Carrier Proteins
  • Proteinase Inhibitory Proteins, Secretory
  • SPINK5 protein, human
  • Serine Peptidase Inhibitor Kazal-Type 5
  • Tissue Kallikreins
Topics
  • Carrier Proteins (analysis)
  • Child
  • Enzyme-Linked Immunosorbent Assay
  • Epidermis (chemistry)
  • Female
  • Humans
  • Immunohistochemistry
  • Proteinase Inhibitory Proteins, Secretory
  • Serine Peptidase Inhibitor Kazal-Type 5
  • Skin Diseases, Genetic (metabolism, pathology)
  • Syndrome
  • Tissue Kallikreins (analysis, blood, physiology)

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