Abstract | UNLABELLED:
Nasopharyngeal carcinoma (NC), especially the undifferenciated type, is a rare malignant disease. Prevalence is high in Southeast Asia and North Africa. OBJECTIVES: MATERIAL AND METHODS: RESULTS: Nine phase III randomised trials, testing the combination of chemotherapy and radiotherapy in nasopharyngeal carcinoma were found. There us increasing evidence attesting to the beneficial effect of adding of chemotherapy to radiotherapy in the treatment of locally advanced disease (stage III and IV), especially concurrent chemo-radiation, considering the benefit in terms of overall survival. Associations containing cisplatin proved to be most effective. New molecules ( capecitabine, taxanes, gemcitabine...) are currently in the course of testing, in phase II studies, for recurrent and metastatic NC, for which there is not still standard treatment. CONCLUSION:
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Authors | H M'Rabti, Y Sbiti, S Afqir, S Boutayeb, H Errihani |
Journal | Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris
(Ann Otolaryngol Chir Cervicofac)
Vol. 123
Issue 2
Pg. 59-64
(Apr 2006)
ISSN: 0003-438X [Print] France |
Vernacular Title | La chimiothérapie dans les cancers du cavum. |
PMID | 16733467
(Publication Type: English Abstract, Journal Article, Review)
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Topics |
- Humans
- Nasopharyngeal Neoplasms
(drug therapy)
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