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Improved microcirculatory effect of D-allose on hepatic ischemia reperfusion following partial hepatectomy in cirrhotic rat liver.

Abstract
D-allose, one of the rare sugars produced from D-psicose, has been shown to be effective against reperfusion injury after ischemia and partial hepatectomy in cirrhotic rat liver by improving remnant liver blood flow and survival rates, and decreasing liver enzyme levels and liver tissue injury levels. These findings demand further study of the clinical implications of this sugar in view to the advancing fields of liver surgery and transplantation.
AuthorsMohammad Akram Hossain, Hisao Wakabayashi, Kunihiko Izuishi, Keiichi Okano, Shinichi Yachida, Masaaki Tokuda, Ken Izumori, Hajime Maeta
JournalJournal of bioscience and bioengineering (J Biosci Bioeng) Vol. 101 Issue 4 Pg. 369-71 (Apr 2006) ISSN: 1389-1723 [Print] Japan
PMID16716947 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • psicose
  • Fructose
  • allose
  • Glucose
  • Bilirubin
Topics
  • Animals
  • Bilirubin (chemistry)
  • Fibrosis (pathology)
  • Fructose (metabolism)
  • Glucose (chemistry)
  • Hemodynamics
  • Hepatectomy
  • Liver (metabolism, pathology)
  • Microcirculation
  • Rats
  • Reperfusion Injury
  • Time Factors

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