Treatment of superficial surgical wounds after removal of seborrheic keratoses: a single-blinded randomized-controlled clinical study.

Abstract

BACKGROUND:

For the treatment of superficial surgical wounds, there are a number of options, including topical antibiotic ointments, dressings, and specialized wound care materials, such as hydrocolloid dressings.

OBJECTIVE:

To evaluate the wound-healing activity of a commercially available hydrocolloid wound dressing (Avery H2460, Avery Dennison, Turnhout, Belgium) in comparison with a control treatment (Fucidine cream with Cutiplast sterile dressing) in superficial wounds after surgical removal of seborrheic keratoses.

METHODS:

In a single-blinded, randomized, controlled trial, the hydrocolloid wound dressing (Avery H2460) was compared with healing by secondary intention as a control. Sixteen patients between 18 and 80 years of age with seborrheic keratoses were enrolled. Wound healing was evaluated after 7 and 10 days and then daily until complete closure of the wound area. In 7 of 16 patients, biopsies were taken after 14 days of reepithelization.

RESULTS:

The hydrocolloid wound dressing (Avery H2460) induced a significantly (p<.05) faster healing (median: 8.5 days) in comparison with the control treatment (median: 10 days). The histologic investigations showed no significant differences for the investigated parameters in both groups.

CONCLUSION:

The faster healing in comparison with the control treatment supports the use of the hydrocolloid wound dressing (Avery H2460) for the treatment of superficial surgical wounds.

• Authors: Steven Goetze, Mirjana Ziemer, Martin Kaatz, Roger D A Lipman, Peter Elsner
• Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 32 Issue 5 Pg. 661-8 (May 2006) ISSN: 1076-0512 [Print] United States
• PMID: 16706761 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)

Topics

• Bandages, Hydrocolloid
• Female
• Humans
• Keratosis, Seborrheic (physiopathology, surgery)
• Male
• Middle Aged
• Single-Blind Method
• Wound Healing