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Inhibition of rotavirus and enterovirus infections by tea extracts.

Abstract
Epigallocatechin gallate from green tea and theaflavin digallate from black tea inhibited infections of cultured rhesus monkey kidney MA 104 cells with rotaviruses and enteroviruses. Their antiviral effects were maximally induced when directly added to virus, and their pre- and post-treatment of the cells produced much weak antiviral activity. Antiviral activity of the extracts therefore seems to be attributable to interference with virus adsorption.
AuthorsA Mukoyama, H Ushijima, S Nishimura, H Koike, M Toda, Y Hara, T Shimamura
JournalJapanese journal of medical science & biology (Jpn J Med Sci Biol) Vol. 44 Issue 4 Pg. 181-6 (Aug 1991) ISSN: 0021-5112 [Print] Japan
PMID1668240 (Publication Type: Journal Article)
Chemical References
  • Antiviral Agents
  • Biflavonoids
  • Tea
  • theaflavin
  • Catechin
  • epigallocatechin gallate
Topics
  • Animals
  • Antiviral Agents (pharmacology)
  • Biflavonoids
  • Catechin (analogs & derivatives, pharmacology)
  • Cell Line
  • Enterovirus (drug effects)
  • Rotavirus (drug effects)
  • Tea (chemistry)
  • Virus Replication (drug effects)

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